Impact of Primary Tumour Location and Early Tumour Shrinkage on Outcomes in Patients with RAS Wild-Type Metastatic Colorectal Cancer Following First-Line FOLFIRI Plus Panitumumab

Author:

Köhne Claus-Henning,Karthaus Meinolf,Mineur Laurent,Thaler Josef,Van den Eynde Marc,Gallego JavierORCID,Koukakis Reija,Berkhout Marloes,Hofheinz Ralf-Dieter

Funder

Amgen (Europe) GmbH

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference31 articles.

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2. National Comprehensive Cancer Network. Clinical practice guidelines in oncology: colon cancer. Version 2. 2019. https://www.nccn.org/professionals/physician_gls/pdf/colon_blocks.pdf. Accessed 13 June 2019.

3. Kohne CH, Hofheinz R, Mineur L, Letocha H, Greil R, Thaler J, et al. First-line panitumumab plus irinotecan/5-fluorouracil/leucovorin treatment in patients with metastatic colorectal cancer. J Cancer Res Clin Oncol. 2012;138:65–72.

4. Karthaus M, Hofheinz R-D, Mineur L, Letocha H, Greil R, Thaler J, et al. Impact of tumour RAS/BRAF status in a first-line study of panitumumab + FOLFIRI in patients with metastatic colorectal cancer. Br J Cancer. 2016;115:1215–22.

5. European Medicines Agency. Vectibix® (panitumumab): summary of product characteristics. 2018. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000741/WC500047710.pdf. Accessed 13 June 2019.

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