Interpretations of the Term “Actionable” when Discussing Genetic Test Results: What you Mean Is Not What I Heard

Author:

Gornick Michele C.12,Ryan Kerry A.1,Scherer Aaron M.3,Scott Roberts J.14,De Vries Raymond G.15,Uhlmann Wendy R.126

Affiliation:

1. Center for Bioethics and Social Sciences in Medicine; University of Michigan Medical School; 2800 Plymouth Road Building 14, G016 Ann Arbor MI 48109-2800 USA

2. Department of Internal Medicine; University of Michigan Medical School; Ann Arbor MI USA

3. Department of Internal Medicine; University of Iowa Carver College of Medicine; Iowa City IA USA

4. Department of Health Behavior & Health Education; School of Public Health; University of Michigan; Ann Arbor MI USA

5. Department of Learning Health Sciences; University of Michigan Medical School; Ann Arbor MI USA

6. Department of Human Genetics; University of Michigan Medical School; Ann Arbor MI USA

Funder

National Human Genome Research Institute

Publisher

Wiley

Subject

Genetics (clinical)

Reference51 articles.

1. Incidental findings in clinical genomics: a clarification;American College of Medical Genetics and Genomics;Genetics in Medicine,2013

2. Development and validation of the JAX Cancer Treatment Profile™ for detection of clinically actionable mutations in solid tumors;Ananda;Experimental and Molecular Pathology,2015

3. Saying what you mean, meaning what you say: language, interaction and interpretation;Astor;Journal of Analytical Psychology,2011

4. Processes and preliminary outputs for identification of actionable genes as incidental findings in genomic sequence data in the clinical sequencing exploratory research consortium;Berg;Genetics in Medicine,2013

5. Health literacy interventions and outcomes: an updated systematic review;Berkman;Evidence report/technology assessment,2011

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