Treatment of Chronic Hepatitis C with the First-Generation Protease Inhibitor Telaprevir: Its Efficacy and Resistance Mutations
Publisher
Springer Singapore
Reference16 articles.
1. Lin K, Perni RB, Kwong AD, Lin C. VX-950, a novel hepatitis C virus (HCV) NS3-4A protease inhibitor, exhibits potent antiviral activities in HCV replicon cells. Antimicrob Agents Chemothr. 2006;50:1813–22. 2. Reesink HW, Zeuzem S, Weegink CJ, Forestier N, van Vliet A, et al. Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a phase Ib, placebo-controlled, randomized study. Gastroenterology. 2006;131:997–1002. 3. Sarrazin C, Kieffer TL, Bartels D, Hanzelka B, Müh U, Welker M, et al. Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir. Gastroenterology. 2007;132:1767–77. 4. McHutchison JG, Everson GT, Gordon SC, Jacobson IM, Sulkowski M, Kauffman R, et al. Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection. N Engl J Med. 2009;360:1827–38. 5. Sarrazin, Rouzier R, Wagner F, Forestier N, Larrey D, Gupta SK, et al. SCH503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders. Gastroenterology. 2007;132:1270–8.
|
|