Genomics and Drug-Metabolizing Enzymes and Its Application in Drug Delivery: Evaluating the Influence of the Microbiome
Author:
Gupta Sheeba Varghese
Publisher
Springer Singapore
Reference115 articles.
1. Williams JA, Hyland R, Jones BC, Smith DA, Hurst S, Goosen TC, Peterkin V, Koup JR, Ball SE (2004) Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios. Drug Metab Dispos 32(11):1201–1208
2. Coon MJ (2005) Cytochrome P450: nature’s most versatile biological catalyst. Annu Rev Pharmacol Toxicol 45:1–25
3. Guengerich FP, Rendic S (2010) Update information on drug metabolism systems-2009, part I. Curr Drug Metab 11(1):1–3
4. Goldstein JA, Faletto MB (1993) Advances in mechanisms of activation and deactivation of environmental chemicals. Environ Health Perspect 100:169–176
5. Fura A, Shu YZ, Zhu M, Hanson RL, Roongta V, Humphreys WG (2004) Discovering drugs through biological transformation: role of pharmacologically active metabolites in drug discovery. J Med Chem 47(18):4339–4351