Prospective randomized controlled trial of postoperative early intravesical chemotherapy with pirarubicin (THP) for solitary non-muscle invasive bladder cancer comparing single and two-time instillation

Author:

Tanimoto Ryuta,Saika Takashi,Ebara Shin,Kobayashi Yasuyuki,Nasu Ryoji,Yamada Daisuke,Takamoto Hitoshi,Miyaji Yoshiyuki,Nasu Yasutomo,Tsushima Tomoyasu,Kumon Hiromi

Funder

OURG

Publisher

Springer Science and Business Media LLC

Subject

Urology

Reference18 articles.

1. Sylvester RJ, Oosterlinck W, Holmang S, Sydes MR, Birtle A, Gudjonsson S, De Nunzio C, Okamura K, Kaasinen E, Solsona E, Ali-El-Dein B, Tatar CA, Inman BA, N’Dow J, Oddens JR, Babjuk M (2016) Systematic review and individual patient data meta-analysis of randomized trials comparing a single immediate instillation of chemotherapy after transurethral resection with transurethral resection alone in patients with stage pTa-pT1 urothelial carcinoma of the bladder: which patients benefit from the instillation? Eur Urol 69(2):231–244. https://doi.org/10.1016/j.eururo.2015.05.050

2. Kang M, Jeong CW, Kwak C, Kim HH, Ku JH (2016) Single, immediate postoperative instillation of chemotherapy in non-muscle invasive bladder cancer: a systematic review and network meta-analysis of randomized clinical trials using different drugs. Oncotarget 7(29):45479–45488. https://doi.org/10.18632/oncotarget.9991

3. De Nunzio C, Carbone A, Albisinni S, Alpi G, Cantiani A, Liberti M, Tubaro A, Iori F (2011) Long-term experience with early single mitomycin C instillations in patients with low-risk non-muscle-invasive bladder cancer: prospective, single-centre randomised trial. World J Urol 29(4):517–521. https://doi.org/10.1007/s00345-011-0691-2

4. Gudjonsson S, Adell L, Merdasa F, Olsson R, Larsson B, Davidsson T, Richthoff J, Hagberg G, Grabe M, Bendahl PO, Mansson W, Liedberg F (2009) Should all patients with non-muscle-invasive bladder cancer receive early intravesical chemotherapy after transurethral resection? The results of a prospective randomised multicentre study. Eur Urol 55(4):773–780. https://doi.org/10.1016/j.eururo.2009.01.006

5. Barghi MR, Rahmani MR, Hosseini Moghaddam SM, Jahanbin M (2006) Immediate intravesical instillation of mitomycin C after transurethral resection of bladder tumor in patients with low-risk superficial transitional cell carcinoma of bladder. Urol J 3(4):220–224

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