Second-line treatment for metastatic clear cell renal cell cancer: experts’ consensus algorithms

Author:

Rothermundt C.,von Rappard J.,Eisen T.,Escudier B.,Grünwald V.,Larkin J.,McDermott D.,Oldenburg J.,Porta C.,Rini B.,Schmidinger M.,Sternberg C. N.,Putora P. M.

Funder

Pfizer

GlaxoSmithKline Australia

Novartis

AstraZeneca

Bayer

Roche

Bristol-Myers Squibb Canada

AVEO

Astellas Pharma US

Merck

Novartis Pharma

Pierre Fabre

Publisher

Springer Science and Business Media LLC

Subject

Urology

Reference24 articles.

1. Escudier B, Porta C, Schmidinger M, Algaba F, Patard JJ, Khoo V, Eisen T, Horwich A, Group EGW (2014) Renal cell carcinoma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 25(3):49–56. doi: 10.1093/annonc/mdu259

2. Ouzaid I, Rini B (2014) Words of wisdom: re: Pazopanib versus sunitinib in metastatic renal-cell carcinoma. Eur Urol 65(3):667–668. doi: 10.1016/j.eururo.2013.11.023

3. Rothermundt C, Bailey A, Cerbone L, Eisen T, Escudier B, Gillessen S, Grunwald V, Larkin J, McDermott D, Oldenburg J, Porta C, Rini B, Schmidinger M, Sternberg C, Putora PM (2015) Algorithms in the first-line treatment of metastatic clear cell renal cell carcinoma-analysis using diagnostic nodes. Oncologist 20(9):1028–1035. doi: 10.1634/theoncologist.2015-0145

4. Rini BI, Escudier B, Tomczak P, Kaprin A, Szczylik C, Hutson TE, Michaelson MD, Gorbunova VA, Gore ME, Rusakov IG, Negrier S, Ou YC, Castellano D, Lim HY, Uemura H, Tarazi J, Cella D, Chen C, Rosbrook B, Kim S, Motzer RJ (2011) Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet 378(9807):1931–1939. doi: 10.1016/s0140-6736(11)61613-9

5. Hutson TE, Escudier B, Esteban E, Bjarnason GA, Lim HY, Pittman KB, Senico P, Niethammer A, Lu DR, Hariharan S, Motzer RJ (2014) Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma. J Clin Oncol 32(8):760–767. doi: 10.1200/JCO.2013.50.3961

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