Efficacy and safety of sofosbuvir–velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial

Author:

Takehara TetsuoORCID,Sakamoto Naoya,Nishiguchi Shuhei,Ikeda Fusao,Tatsumi Tomohide,Ueno Yoshiyuki,Yatsuhashi Hiroshi,Takikawa Yasuhiro,Kanda Tatsuo,Sakamoto Minoru,Tamori Akihiro,Mita Eiji,Chayama Kazuaki,Zhang Gulan,De-Oertel Shampa,Dvory-Sobol Hadas,Matsuda Takuma,Stamm Luisa M.,Brainard Diana M.,Tanaka Yasuhito,Kurosaki Masayuki

Funder

Gilead Sciences

Publisher

Springer Science and Business Media LLC

Subject

Gastroenterology

Reference18 articles.

1. American Association for the Study of Liver Diseases and the Infectious Diseases Society of America. HCV guidance: recommendations for testing, managing, and treating hepatitis C. http://www.hcvguidelines.org/ . Accessed 13 June 2018.

2. Charlton M, Everson GT, Flamm SL, et al. Ledipasvir and sofosbuvir plus ribavirin for treatment of HCV infection in patients with advanced liver disease. Gastroenterology. 2015;149:649–59.

3. Manns M, Samuel D, Gane EJ, et al. Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial. Lancet Infect Dis. 2016;16:685–97.

4. Curry MP, O’Leary JG, Bzowej N, et al. Sofosbuvir and velpatasvir for HCV in patients with decompensated cirrhosis. N Engl J Med. 2015;373:2618–28.

5. The Japan Society of Hepatology (JSH), Guidelines for the management of hepatitis C virus infection: edition 6.1, full version [Japanese]. 2018. http://www.jsh.or.jp/files/uploads/R1__6.pdf . Accessed 13 June 2018.

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