Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment-Reference-Cited by-同舟云学术

Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment

Published:2009-02-13 Issue:3 Volume:44 Page:197-203
ISSN:0944-1174
Container-title:Journal of Gastroenterology
language:en
Short-container-title:J Gastroenterol

Author:

Uchiyama Kan,Nakamura Makoto,Kubota Takahiro,Yamane Tateki,Fujise Kiyotaka,Tajiri Hisao

Publisher

Springer Science and Business Media LLC

Subject

Gastroenterology

Link

http://link.springer.com/content/pdf/10.1007/s00535-008-2307-1.pdf

Reference27 articles.

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2. Ansari A, Hassan C, Dulay J, Marinaki A, Shobowale-Bakre EM, Seed P, et al. Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease. Aliment Pharmacol Ther 2002;16:1743–1750.

3. Lennard L. TPMT in the treatment of Crohn’s disease with azathioprine. Gut 2002;51:143–146.

4. Kubota T, Chiba K. Frequencies of thiopurine S-methyltransferase mutant alleles (TPMT*2, *3A, *3B, *3C) in 151 healthy Japanese subjects and the inheritance of TPMT*3C in the family of a propositus. Br J Clin Pharmacol 2001;51: 475–477.

5. Ishiguro A, Kubota T, Soya Y, Sasaki H, Yagyu O, Takarada Y, et al. High-throughput detection of multiple genetic polymorphisms influencing drug metabolism with mismatch primers in allele specific polymerase chain reaction. Anal Biochem 2005;337: 256–261.

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