Indoleamine 2,3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis

Author:

Wu Chaofeng,Li Junjie,Jia Hui,Zhao Jiamin,Qin Mengchen,Shi Hao,Liu Chang,Lin Jiajie,Cai Min,Gu Yong,Liu Bin,Gao LeiORCID

Funder

National Natural Science Foundation of China

Guangdong Basic and Applied Basic Research Foundation

the Outstanding Youth Development Scheme project of Southern Medical University

Young Elite Scientists Sponsorship Program by CACM

Hainan Province Science and Technology Special Fund

Publisher

Springer Science and Business Media LLC

Reference58 articles.

1. Shiha G, Korenjak M, Eskridge W, et al. Redefining fatty liver disease: an international patient perspective. Lancet Gastroenterol. 2021;6:73–9.

2. Devarbhavi H, Asrani SK, Arab JP, et al. Global burden of liver disease: 2023 update. J Hepatol. 2023;79:516–37.

3. Friedman SL, Neuschwander-Tetri BA, Rinella M, et al. Mechanisms of NAFLD development and therapeutic strategies. Nat Med. 2018;24:908–22.

4. Powell EE, Wong VW, Rinella M. Non-alcoholic fatty liver disease. Lancet. 2021;397:2212–24.

5. Wong VW, Chitturi S, Wong GL, et al. Pathogenesis and novel treatment options for non-alcoholic steatohepatitis. Lancet Gastroenterol. 2016;1:56–67.

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