Affiliation:
1. Institute of Molecular Biology Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria
Abstract
Ehrlich Ascites Tumour cells were irradiated with UV-light to crosslink DNA to proteins in vivo. The DNA fragments associated with the nuclear lamina were purified and characterized. The results of the Cot analysis and the hybridization experiments suggest that the DNA fragments attached to the nuclear lamina although containing the entire complexity of genomic DNA are enriched in some highly repeated sequences.
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
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