Intratympanic Therapies for Menière’s Disease

Author:

Miller Matthew W.,Agrawal Yuri

Publisher

Springer Science and Business Media LLC

Subject

Clinical Neurology,Otorhinolaryngology,Immunology and Allergy,Surgery

Reference29 articles.

1. Schuknecht H. Meniere’s disease: a correlation of symptomatology and pathology. Laryngoscope. 1963;73:651–65.

2. • Casani AP, Cerchiai N, Navari E, Dallan I, Piaggi P, Sellari-Franceschini S. Intratympanic gentamicin for meniere’s disease: short- and long-term follow-up of two regimens of treatment. Otolaryngol Head Neck Surg. 2014;150(5):847–52. This retrospective study compares the previous higher-dose intratympanic gentamicin regimen with a more recently used lower‐dose treatment. High control rates were achieved.

3. • Quaglieri S, Gatti O, Rebecchi E, Manfrin M, Tinelli C, Mira E, et al. Intratympanic gentamicin treatment “as needed” for meniere’s disease. Long-term analysis using the Kaplan–Meier method. Eur Arch Otorhinolaryngol. 2013;271(6):1443–9. This retrospective study reinforces the notion that patients can be treated with lower doses of intratympanic gentamicin, with repeat doses "as needed" should symptoms persist.

4. • Wasson J, Upile N, Pfleiderer A. Intratympanic gentamicin treatment for unilateral Ménière’s disease: long-term follow up of a proven regime. J Laryngol Otol. 2013;127(1):20–4. This retrospective review is a follow-up of previously published results. Patients were contacted via telephone to survey ongoing symptom control following a high‐dose intratympanic gentamicin protocol.

5. • Walther LE, Huelse R, Blättner K, Bloching MB, Blödow A. Dynamic change of VOR and otolith function in intratympanic gentamicin treatment for Ménière’s disease: case report and review of the literature. Case Rep Otolaryngol. 2013;2013:1–5. This case report describes the timecourse of the objective changes (video head impulse test, oVEMP, cVEMP, and bithermal calorics) in the weeks following a single dose of intratympanic getamicin.

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