Ultrasensitive Detection of Aggregated α-Synuclein in Glial Cells, Human Cerebrospinal Fluid, and Brain Tissue Using the RT-QuIC Assay: New High-Throughput Neuroimmune Biomarker Assay for Parkinsonian Disorders-Reference-Cited by-同舟云学术

Ultrasensitive Detection of Aggregated α-Synuclein in Glial Cells, Human Cerebrospinal Fluid, and Brain Tissue Using the RT-QuIC Assay: New High-Throughput Neuroimmune Biomarker Assay for Parkinsonian Disorders

Published:2019-01-31 Issue:3 Volume:14 Page:423-435
ISSN:1557-1890
Container-title:Journal of Neuroimmune Pharmacology
language:en
Short-container-title:J Neuroimmune Pharmacol

Author:

Manne Sireesha,Kondru Naveen,Hepker Monica,Jin Huajun,Anantharam Vellareddy,Lewis Mechelle,Huang Xuemei,Kanthasamy Arthi,Kanthasamy Anumantha G.

Funder

National Center for Advancing Translational Sciences

National Institutes of Health

Michael J. Fox Foundation for Parkinson's Research

U.S. Department of Defense

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Immunology,Immunology and Allergy,Neuroscience (miscellaneous)

Link

http://link.springer.com/article/10.1007/s11481-019-09835-4/fulltext.html

Reference39 articles.

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3. Bidinosti M, Shimshek DR, Mollenhauer B, Marcellin D, Schweizer T, Lotz GP, Schlossmacher MG, Weiss A (2012) Novel one-step immunoassays to quantify alpha-synuclein: applications for biomarker development and high-throughput screening. J Biol Chem 287:33691–33705

4. Block ML, Zecca L, Hong JS (2007) Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 8:57–69

5. Braak H, Braak E (2000) Pathoanatomy of Parkinson's disease. J Neurol 247(Suppl 2):Ii3–I10

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