Neoadjuvant treatment in solid tumors—the earlier, the better in breast cancer

Author:

Pusch Renate

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Hematology

Reference31 articles.

1. Buzdar AU, Ibrahim NK, Francis D, et al. Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2‑positive operable breast cancer. J Clin Oncol. 2005;23:3676–85. https://doi.org/10.1200/jco.2005.07.032.

2. Gianni L, Eiermann W, Semiglazov V, et al. Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a randomised controlled superiority trial with a parallel HER2-negative cohort. Lancet. 2010;375:377–84. https://doi.org/10.1016/s0140-6736(09)61964-4.

3. Untch M, Loibl S, Bischoff J, et al. Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase III trial. Lancet Oncol. 2012;13:135–44. https://doi.org/10.1016/s1470-2045(11)70397-7.

4. Baselga J, Bradbury I, Eidtmann H, et al. Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase III trial. Lancet. 2012;379:633–40. https://doi.org/10.1016/s0140-6736(11)61847-3.

5. Gianni L, Pienkowski T, Im YH, et al. 5‑year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): a multicentre, open-label, phase II randomised trial. Lancet Oncol. 2016;17:791–800. https://doi.org/10.1016/s1470-2045(16)00163-7.

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