The Search for Single-Domain Antibodies Interacting with the Receptor-Binding Domain of SARS-CoV-2 Surface Protein

Author:

Aripov V. S.,Volkova N. V.,Taranin A. V.,Mechetina L. V.,Chikaev N. A.,Nayakshin A. M.,Nesmeyanova V. S.,Isaeva A. A.,Merkul’eva Yu. A.,Shanshin D. V.,Belenkaya S. V.,Ilyichev A. A.,Shcherbakov D. N.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference12 articles.

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2. Gorchakov AA, Kulemzin SV, Guselnikov SV, Baranov KO, Belovezhets TN, Mechetina LV, Volkova OY, Najakshin AM, Chikaev NA, Chikaev AN, Solodkov PP, Larichev VF, Gulyaeva MA, Markhaev AG, Kononova YV, Alekseyev AY, Shestopalov AM, Yusubalieva GM, Klypa TV, Ivanov AV, Valuev-Elliston VT, Baklaushev VP, Taranin AV. Isolation of a panel of ultra-potent human antibodies neutralizing SARS-CoV-2 and viral variants of concern. Cell Discov. 2021;7(1):96. https://doi.org/10.1038/s41421-021-00340-8

3. Van Bockstaele F, Holz JB, Revets H. The development of nanobodies for therapeutic applications. Curr. Opin. Investig Drugs. 2009;10(11):1212-1224.

4. Esmagambetov IB, Shcheblyakov DV, Egorova DA, Voronina OL, Derkaev AA, Voronina DV, Popova OA, Ryabova EI, Shcherbinin DN, Aksenova EI, Semenov AN, Kunda MS, Ryzhova NN, Zubkova OV, Tukhvatulin AI, Logunov DYu, Naroditsky BS, Borisevich SV, Gintsburg AL. Nanobodies are potential therapeutic agents for the Ebola virus infection. Acta Naturae. 2021;13(4):53-63. https://doi.org/10.32607/actanaturae.11487

5. Detalle L, Stohr T, Palomo C, Piedra PA, Gilbert BE, Mas V, Millar A, Power UF, Stortelers C, Allosery K, Melero JA, Depla E. Generation and characterization of ALX-0171, a potent novel therapeutic nanobody for the treatment of respiratory syncytial virus infection. Antimicrob. Agents Chemother. 2015;60(1):6-13. https://doi.org/10.1128/AAC.01802-15

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