Hepatocytic Apoptosis and Immune Dysfunction in Decompensation of Alcoholic Liver Cirrhosis with Different Grades of Acute-on-Chronic Liver Failure

Author:

Rodina A. S.,Shubina M. E.,Kurbatova I. V.,Topchieva L. V.,Dudanova O. P.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference14 articles.

1. Ivashkin VT, Mayevskaya MV, Pavlov ChS, Sivolap YuP, Lunkov VD, Zharkova MS, Maslennikov RV. Management of adult patients with alcoholic liver disease: clinical guidelines of the Russian Scientific Liver Society. Ross. Zh. Gastroenterol. Gepatol., Koloproktol. 2017;27(6):20-40. https://doi.org/10.22416/1382-4376-2017-27-6-20-40. Russian.

2. Lazebnik LB, Golovanova EV, Tarasova LV, Krivosheev AB, Sas EI, Eremina EYu, Trukhan DI, Hlynova OV, Tsyganova YuV. Adult Alcoholic Liver Disease. Eksp. Klin. Gastroenterol. 2020;(2):4-28. https://doi.org/10.31146/1682-8658-ecg-174-2-4-28. Russian.

3. Bai L, Chen Y, Zheng S, Ren F, Kong M, Liu S, Han Y, Duan Z. Phenotypic switch of human and mouse macrophages and resultant effects on apoptosis resistance in hepatocytes. Innate Immun. 2019;25(3):176-185. https://doi.org/10.1177/1753425919831350

4. Bernardi M, Angeli P, Claria J, Moreau R, Gines P, Jalan R, Caraceni P, Fernandez J, Gerbes AL, O’Brien AJ, Trebicka J, Thevenot T, Arroyo V. Albumin in decompensated cirrhosis: new concepts and perspectives. Gut. 2020;69(6):1127-1138. https://doi.org/10.1136/gutjnl-2019-318843

5. Bernsmeier C, Pop OT, Singanayagam A, Triantafyllou E, Patel VC, Weston CJ, Curbishley S, Sadiq F, Vergis N, Khamri W, Bernal W, Auzinger G, Heneghan M, Ma Y, Jassem W, Heaton ND, Adams DH, Quaglia A, Thursz MR, Wendon J, Antoniades CG. Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK. Gastroenterology. 2015;148(3):603-615.e14. https://doi.org/10.1053/j.gastro.2014.11.045

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