Comparative Study of the Restoring Effect of Metformin, Gonadotropin, and Allosteric Agonist of Luteinizing Hormone Receptor on Spermatogenesis in Male Rats with Streptozotocin-Induced Type 2 Diabetes Mellitus

Author:

Derkach K. V.,Bakhtyukov A. A.,Morina I. Yu.,Romanova I. V.,Bayunova L. V.,Shpakov A. O.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference15 articles.

1. Aly HAA. Mitochondria-mediated apoptosis induced testicular dysfunction in diabetic rats: ameliorative effect of resveratrol. Endocrinology. 2021;162(4):bqab018. doi: https://doi.org/10.1210/endocr/bqab018

2. Bakhtyukov AA, Derkach KV, Gureev MA, Dar’in DV, Sorokoumov VN, Romanova IV, Morina IY, Stepochkina AM, Shpakov AO. Comparative study of the steroidogenic effects of human chorionic gonadotropin and thieno[2,3-D]pyrimidinebased allosteric agonist of luteinizing hormone receptor in young adult, aging and diabetic male rats. Int. J. Mol. Sci. 2020;21(20):7493. doi: https://doi.org/10.3390/ijms21207493.

3. Derkach KV, Bondareva VM, Chistyakova OV, Berstein LM, Shpakov AO. The effect of long-term intranasal serotonin treatment on metabolic parameters and hormonal signaling in rats with high-fat diet/low-dose streptozotocin-induced type 2 diabetes. Int. J. Endocrinol. 2015;2015:245459. doi: https://doi.org/10.1155/2015/245459

4. Derkach KV, Romanova IV, Bakhtyukov AA, Morina IY, Dar’in DV, Sorokoumov VN, Shpakov AO. The effect of lowmolecular- weight allosteric agonist of luteinizing hormone receptor on functional state of the testes in aging and diabetic rats. Bull. Exp. Biol. Med. 2021;171(1):81-86. doi: https://doi.org/10.1007/s10517-021-05177-5

5. Ding GL, Liu Y, Liu ME, Pan JX, Guo MX, Sheng JZ, Huang HF. The effects of diabetes on male fertility and epigenetic regulation during spermatogenesis. Asian J. Androl. 2015;17(6):948-953. doi: https://doi.org/10.4103/1008-682X.150844

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