Considerations for the pre-clinical evaluation of new psychiatric drugs: A case study with phenothiazine-like tranquilizers

Author:

Irwin Samuel

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference36 articles.

1. Ayd, F. J.: Fluphenazine: Its spectrum of therapeutic application and clinical results in psychiatric patients. Curr. ther. Res. 1, 41?48 (1959).

2. ?: Phenothiazine tranquilizers: Eight years of Development. Med. Clin. N. Amer. 45, 1027?1040 (1961).

3. Brodie, B. B., and R. P. Maickel: Comparative biochemistry of drug metabolism. In: Proc. First Internat. Pharmacol. Meeting, vol. 6, pp. 299?324. New York: Pergamon Press 1962.

4. Burns, J. J.: Species differences and individual variations in drug metabolism. Ibid: pp. 277?288 (1962).

5. Cole, J. O., and R. E. Edwards: Prediction of clinical effects of psychotropic drugs from animal data. In: Animal behavior and drug action, Ed., H. Steinberg, pp. 286?297. London: J. & A. Churchill, Ltd. 1964.

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