Management of Adverse Effects of Second-generation Antipsychotics in Youth

Author:

Raffin Marie,Gianitelli Marianna,Consoli Angèle,Bonnot Olivier,Menard Marie-Line,Askenazy Florence,Laurent Claudine,Cohen David

Publisher

Springer Science and Business Media LLC

Subject

Psychiatry and Mental health,Clinical Psychology

Reference78 articles.

1. Cohen D, Raffin M, Canitano R, Bodeau N, Bonnot O, Périsse D, et al. Risperidone or aripiprazole in children and adolescents with autism and/or intellectual disability: A Bayesian meta-analysis of efficacy and secondary effects. Res Autism Spectr Dis. 2013;7:167–75.

2. Olfson M, Blanco C, Liu L, Moreno C, Laje G. National trends in the outpatient treatment of children and adolescents with antipsychotic drugs. Arch Gen Psychiatry. 2006;63(6):679–85.

3. Acquaviva E, Legleye S, Auleley GR, Deligne J, Carel D, Falissard BB. Psychotropic medication in the French child and adolescent population: prevalence estimation from health insurance data and national self-report survey data. BMC Psychiatry. 2009;9:72.

4. Woods SW, Martin A, Spector SG, McGlashan TH. Effects of development on olanzapine-associated adverse events. J Am Acad Child Adolesc Psychiatry. 2002;41(12):1439–46. This is a large pharmacovigilance study on more than 4 million olanzapine prescriptions in the USA. Authors showed that the risk of complaints for, weight gain, sedation, dystonia and tardive dyskinesia is 4 to 5 times more frequent among children than adults. The risk for sedation is two times higher among adolescent than adults and regarding weight gain the risk of complaints is tree time more frequent among adolescent than adults.

5. Correll CU, Manu P, Olshanskiy V, Napolitano B, Kane JM, Malhotra AK. Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents. JAMA. 2009;302(16):1765–73.

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