A hyman hybrid hybridoma producing a bispecific monoclonal antibody that can target tumor cells for attack by Pseudomonas aeruginosa exotoxin A

Author:

Honda Susumu,Ichimori Yuzo,Iwasa Susumu

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Clinical Biochemistry,Biomedical Engineering,Bioengineering,Biotechnology

Reference22 articles.

1. Corvalan JRF, Smith W, Gore VA and Brandon DR (1987) Specific in vitro and in vivo drug localisation to tumor cells using a hybrid-hybrid monoclonal antibody recognising both carcinoembryonic antigen (CEA) and vinca alkaloids. Cancer Immunol. Immunother. 24: 133?137.

2. Corvalan JRF, Smith W and Gore VA (1988) Tumour therapy with vinca alkaloids targeted by a hybrid-hybrid monoclonal antibody recognising both CEA and vinca alkaloids. Int. J. Cancer Supplement 2: 22?25.

3. Glennie MJ, McBride HM, Worth AT and Stevenson GT (1987) Preparation and performance of bispecific F(ab'?)2 antibody containing thioether-linked Fab'? fragments. J. Immunol. 139: 2367?2375.

4. Hämmerling U, Aoki T, Harven E, Boyse EA and Old LJ (1968) Use of hybrid antibody with anti-?G and anti-ferritin specificities in locating cell surface antigens by electron microscopy. J. Exp. Med. 128: 1461?1469.

5. Ichimori Y, Harada K, Hitotsumachi S and Tsukamoto K (1987) Establishment of hybridoma secreting human monoclonal antibody against hepatitis B virus surface antigen. Biochem. Biophys. Res. Commun. 142: 805?812.

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