Terfenadine: A mixture of equipotent antihistamine enantiomers without a clear ‘isomeric ballast’

Author:

Zhang Ming-Qiang,Timmerman Henk

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,Toxicology,Pharmacy,General Medicine,Pharmacology (medical),Pharmacology

Reference30 articles.

1. Carr AA, Meyer DR. Synthesis of terfenadine. Arzneimittelforschung/Drug Res 1982;32:1157–9.

2. Kinsolving CR, Munro NL, Carr AA. Separation of the CNS and H1 receptor effects of antihistamine agents. Pharmacologist 1973;15:221.

3. McTavish D, Goa KL, Ferrill M. Terfenadine: an updated review of its pharmacological properties and therapeutic efficacy. Drugs 1990;39:552–74.

4. Makino S, Ikemori R, Fukuda T, Miyamoto T, Suzuki S. Clinical evaluation of terfenadine in bronchial asthma —comparison with ketotifen in a multi-center double-blind study. Rinsho lyaku 1988;4:1687–722.

5. Rafferty P, Jackson L, Smith R, Holgate ST. Terfenadine in the treatment of grass pollen sensitive asthmatics during the hay fever season. Br J Clin Pharmacol 1988;25:623p-4p.

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