A preliminary study of the pharmacodynamics and pharmacokinetics of a novel enkephalin analogue [Tyr-D.Arg-Gly-Phe(4NO2)�Pro�NH2 (BW443C)] in healthy volunteers

Author:

Posner J.,Dean K.,Jeal S.,Moody S. G.,Peck A. W.,Rutter G.,Telekes A.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference10 articles.

1. Ferreira SH, Nakamura M (1979) Prostaglandin hyperalgesia: The peripheral analgesic activity of morphine, enkephalins and opioid antagonists. Prostaglandins 18: 191?200

2. Follenfant RL, Hardy GW, Lowe LA, Smith TW (1987) Antinociceptive effects of a novel, peripherally acting opioid peptide, Tyr·D·Arg·Gly·Phe(4NO2)·Pro·NH2 (BW443C). Br J Pharmacol 90: 68P

3. Lorenzetti BB, Ferreira SH (1987) On the mode of analgesic action of Tyr·D·Arg·Gly·Phe(4NO2)·Pro·NH2 (BW443C). Br J Pharmacol 90: 69P

4. Adcock JJ, Allan G, Richardson PJ, Schneider C, Smith TW (1987) Antitussive effects and inhibition of vagal sensory nerve activity by Tyr·D·Arg·Gly·Phe(4NO2)·Pro·NH2 (BW443C). Br J Pharmacol 90: 143P

5. Smith TW, Buchan P, Parsons DN, Wilkinson S (1982) Peripheral antinociceptive effects of N-methyl morphine. Life Sci 31: 1205?1208

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