Diazepam: Prediction of pharmacodynamics from pharmacokinetics

Author:

Ellinwood E. H.,Nikaido A.,Heatherly D.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference9 articles.

1. Ellinwood EH Jr, Linnoila M, Molter DW (1981) Onset of peak impairment after diazepam and after alcohol. Clin Pharmacol Ther 30:534?538

2. Ellinwood EH Jr, Linnoila M, Easler ME, Molter DW (1983) Profile of acute tolerance to three sedative anxiolytics. Psychopharmacology 79:137?141

3. Ellinwood EH Jr, Easler ME, Linnoila M, Molter DW, Heatherly DG, Bjornson TD (1984) Effects of oral contraceptives on diazepam-induced impairment. Clin Pharmacol Ther (in press)

4. Gibaldi M, Perrier D (1975) Pharmacokinetics. Marcel Dekker, New York, pp 89?95

5. Jack ML, Colburn WA, Spirt NM, Bautz G, Zanko M, Horst WD, O'Brien A (1983) A pharmacokinetic/pharmacodynamic/receptor binding model to predict the onset and duration of pharmacological activity of the benzodiazepines. Prog Neuropsychopharmacol Biol Psychiatry 7:5?6

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