Incorporation of digital gene expression profiling for cell-of-origin determination (Lymph2Cx testing) into the routine work-up of diffuse large B cell lymphoma

Author:

Robetorye Ryan S.ORCID,Ramsower Colleen A.,Rosenthal Allison C.,Yip Tameson K.,Wendel Spiczka Amy J.,Glinsmann-Gibson Betty J.,Rimsza Lisa M.

Funder

Center for Individualized Medicine, Mayo Clinic

Division of Cancer Epidemiology and Genetics, National Cancer Institute

Publisher

Springer Science and Business Media LLC

Subject

Hematology,Histology,Pathology and Forensic Medicine

Reference26 articles.

1. Swerdlow S, Campo E, Harris NL et al (2017) WHO classification of tumours of haematopoietic and lymphoid tissues revised, 4th edn. Interntional Agency for Research on Cancer, Lyon

2. Swerdlow SH, World Health Organization., and International Agency for Research on Cancer (2008) WHO classification of tumours of haematopoietic and lymphoid tissues, 4th edn. World Health Organization classification of tumours. International Agency for Research on Cancer, Lyon

3. Alizadeh AA, Eisen MB, Davis RE et al (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403:503–511. https://doi.org/10.1038/35000501

4. Lenz G, Wright G, Dave SS et al (2008) Stromal gene signatures in large-B-cell lymphomas. N Engl J Med 359:2313–2323. https://doi.org/10.1056/NEJMoa0802885

5. Rosenwald A, Wright G, Chan WC et al (2002) The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N Engl J Med 346:1937–1947. https://doi.org/10.1056/NEJMoa012914

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