An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT1 Angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies-Reference-Cited by-同舟云学术

An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT1 Angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies

Published:2010-07-10 Issue:9 Volume:24 Page:749-758
ISSN:0920-654X
Container-title:Journal of Computer-Aided Molecular Design
language:en
Short-container-title:J Comput Aided Mol Des

Author:

Agelis George,Roumelioti Panagiota,Resvani Amalia,Durdagi Serdar,Androutsou Maria-Eleni,Kelaidonis Konstantinos,Vlahakos Demetrios,Mavromoustakos Thomas,Matsoukas John

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry,Computer Science Applications,Drug Discovery

Link

http://link.springer.com/content/pdf/10.1007/s10822-010-9371-3.pdf

Reference61 articles.

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