Holistic in silico developability assessment of novel classes of small proteins using publicly available sequence-based predictors-Reference-Cited by-同舟云学术

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Holistic in silico developability assessment of novel classes of small proteins using publicly available sequence-based predictors

Published:2024-08-20 Issue:1 Volume:38 Page:
ISSN:0920-654X
Container-title:Journal of Computer-Aided Molecular Design
language:en
Short-container-title:J Comput Aided Mol Des

Author:

Pais Daniel A. M.^ORCID,Mayer Jan-Peter A.,Felderer Karin,Batalha Maria B.^ORCID,Eichner Timo,Santos Sofia T.,Kumar Raman,Silva Sandra D.,Kaufmann Hitto

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1007/s10822-024-00569-x.pdf

Reference53 articles.

1. Kesik-Brodacka M (2018) Progress in biopharmaceutical development. Biotechnol Appl Biochem 65(3):306–322. https://doi.org/10.1002/bab.1617

2. O’Flaherty R, Bergin A, Flampouri E, Mota LM, Obaidi I, Quigley A, Xie Y, Butler M (2020) Mammalian cell culture for production of recombinant proteins: a review of the critical steps in their biomanufacturing. Biotechnol Adv 43:107552. https://doi.org/10.1016/j.biotechadv.2020.107552

3. Walsh G (2018) Biopharmaceutical benchmarks 2018. Nat Biotechnol 36(12):1136–1145. https://doi.org/10.1038/nbt.4305

4. Shah DK, Betts AM (2013) Antibody biodistribution coefficients: inferring tissue concentrations of monoclonal antibodies based on the plasma concentrations in several preclinical species and human. MAbs 5(2):297–305. https://doi.org/10.4161/mabs.23684

5. Thurber GM, Schmidt MM, Wittrup KD (2008) Antibody tumor penetration: transport opposed by systemic and antigen-mediated clearance. Adv Drug Deliv Rev 60(12):1421–1434. https://doi.org/10.1016/j.addr.2008.04.012

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