How medicinal chemists learned about log P-Reference-Cited by-同舟云学术

How medicinal chemists learned about log P

Published:2018-07-17 Issue:8 Volume:32 Page:809-819
ISSN:0920-654X
Container-title:Journal of Computer-Aided Molecular Design
language:en
Short-container-title:J Comput Aided Mol Des

Author:

Martin Yvonne Connolly

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry,Computer Science Applications,Drug Discovery

Link

http://link.springer.com/article/10.1007/s10822-018-0127-9/fulltext.html

Reference120 articles.

1. Mannhold R, Kubinyi H, Timmerman H (2008) Lipophilicity in drug action and toxicology. In: Pliška V, Testa B, van de Waterbeemd H (ed), vol 4. Wiley

2. Hughes JD (2008) Physiochemical drug properties associated with in vivo toxicological outcomes. Bioorg Med Chem Lett 18:4872–4875

3. Waring MJ (2010) Lipophilicity in drug discovery. Expert Opin Drug Discov 5:235–248

4. Hill AP, Young RJ (2010) Getting physical in drug discovery: a contemporary perspective on solubility and hydrophobicity. Drug Discov Today 15:648–655

5. Arnott JA, Planey SL (2012) The influence of lipophilicity in drug discovery and design. Expert Opin Drug Discov 7:863–875

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis and anti-tumor evaluation of plinabulin derivatives as potential agents targeting β-tubulin;Bioorganic & Medicinal Chemistry Letters;2023-07

2. μPESI-MS/MS System for Screening and Quantitating Drugs in Plasma Samples;Journal of the American Society for Mass Spectrometry;2023-06-20

3. Taking model pursuit seriously;European Journal for Philosophy of Science;2023-05-06

4. Polymer drug conjugates containing memantine, tacrine and cinnamic acid: promising nanotherapeutics for the treatment of Alzheimer’s disease;Journal of Microencapsulation;2023-01-02

5. Synthesis, characterization and biological activity of novel copper complexes containing a β-carboline derivative and amino acids;Dalton Transactions;2023