Energetic basis for drug resistance of HIV-1 protease mutants against amprenavir
Author:
Publisher
Springer Science and Business Media LLC
Subject
Physical and Theoretical Chemistry,Computer Science Applications,Drug Discovery
Link
http://link.springer.com/content/pdf/10.1007/s10822-012-9550-5.pdf
Reference66 articles.
1. Darke PL, Leu CT, Davis LJ, Heimbach JC, Diehl RE, Hill WS, Dixon RA, Sigal IS (1989) Human immunodeficiency virus protease. Bacterial expression and characterization of the purified aspartic protease. J Biol Chem 264:2307–2312
2. Seelmeir S, Schmidt H, Turk V, VonDer Helm K (1988) Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin A. Proc Natl Acad Sci USA 85:6612–6616
3. Mous J, Heimer EP, Le Grice SJJ (1988) Processing protease and reverse transcriptase from human immunodeficiency virus type I polyprotein in Escherichia coli. J Virol 62:1433–1436
4. Hornak V, Okur A, Rizzo RC, Simmerling C (2006) HIV-1 protease flaps spontaneously open and reclose in molecular dynamics simulations. Proc Natl Acad Sci USA 103:915–920
5. Chang CA, Trylska J, Tozzini V, McCammon JA (2007) Binding pathways of ligands to HIV-1 protease: corase-grained and atomistic simulations. Chem Biol Drug Des 69:5–13
Cited by 48 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Multiple Functional Protein–Protein Interaction Interfaces Allosterically Regulate ATP‐Binding in Cyclin‐Dependent Kinase‐1;Proteins: Structure, Function, and Bioinformatics;2024-07-16
2. Elucidating the conformational dynamics of histo-blood group antigens and their interactions with the rotavirus spike protein through computational lens;Journal of Biomolecular Structure and Dynamics;2023-11
3. Decoding drug resistant mechanism of V32I, I50V and I84V mutations of HIV-1 protease on amprenavir binding by using molecular dynamics simulations and MM-GBSA calculations;SAR and QSAR in Environmental Research;2022-10-03
4. Hybrid QM/MM Free-Energy Evaluation of Drug-Resistant Mutational Effect on the Binding of an Inhibitor Indinavir to HIV-1 Protease;Journal of Chemical Information and Modeling;2022-02-25
5. Decoding the Host–Parasite Protein Interactions Involved in Cerebral Malaria Through Glares of Molecular Dynamics Simulations;The Journal of Physical Chemistry B;2022-01-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3