Construction of double suicide genes system controlled by MDR1 promoter with targeted expression in drug-resistant glioma cells

Author:

Zhang Yuan,Wang Cheng-wei,Wang Zhi-gang,Ma Dao-xin,Pan Shun,Zhu Shu-gan,Li Feng,Wang Bo

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Neurology (clinical),Neurology,Oncology

Reference32 articles.

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2. Comerford KM, Wallace TJ, Karhausen J et al (2002) Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. Cancer Res 62:3387–3394

3. Montaudon D, Benchekroun MN, Londos-Gagliardi et al (1990) Chromosomal modification of a rat glioblastoma cell line during the acquisition and reversal of doxorubicin resistance. Anticancer Res 10:1667–1676

4. Ogretmen B, Ahmad R (1999) Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-II B/p65 and c-Fos. Transcription factors and their interaction with the CAAT region. Biochemistry 38:2189–2199

5. Kartner N, Evernden-Porelle D, Bradley G et al (1985) Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature 316:820–823

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