Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells

Author:

Abouantoun Thamara J.,Castellino Robert C.,MacDonald Tobey J.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Neurology (clinical),Neurology,Oncology

Reference16 articles.

1. Giangaspero F, Bigner SH, Kleihues P et al (2000) Medulloblastoma. In: Kleihues P, Cavanee WK (eds) World health organization classification of tumours: pathology and genetics of tumours of the nervous system. International Agency for Research on Cancer, Lyon

2. McLean TW (2003) Medulloblastomas and central nervous system primitive neuroectodermal tumours. Curr Treat Options Oncol 4:499–508

3. Packer RJ, Rood BR, Macdonald TJ (2003) Medulloblastoma: present concepts of stratification into risk groups. Pediatr Neurosurg 39:60–67

4. Abouantoun TJ, MacDonald TJ (2009) Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of pf epidermal growth factor receptor. Mol Cancer Ther 8:1137–1147

5. Koutras AK, Krikelis D, Alexandrou N et al (2007) Brain metastasis in renal cell cancer responding to sunitinib. Anticancer Res 27:4255–4257

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