Circadian regulation of MGMT expression and promoter methylation underlies daily rhythms in TMZ sensitivity in glioblastoma

Author:

Gonzalez-Aponte Maria F.ORCID,Damato Anna R.ORCID,Trebucq Laura LucíaORCID,Simon TatianaORCID,Cárdenas-García Sandra P.ORCID,Cho KevinORCID,Patti Gary J.ORCID,Golombek Diego A.ORCID,Chiesa Juan JoséORCID,Rubin Joshua B.ORCID,Herzog Erik D.ORCID

Funder

National Institutes of Health

Washington University Siteman Cancer Center

Universidad Nacional de Quilmes

Agencia Nacional de Promoción Científica y Tecnológica de Argentina

Publisher

Springer Science and Business Media LLC

Reference46 articles.

1. Llaguno SA et al (2009) Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell 15(1):45–56. https://doi.org/10.1016/j.ccr.2008.12.006

2. Zong H, Parada LF, Baker SJ (2015) Cell of origin for malignant gliomas and its implication in therapeutic development. Cold Spring Harb Perspect Biol 7(5):a020610. https://doi.org/10.1101/cshperspect.a020610

3. Tamimi AF, Juweid M (2017) Epidemiology and outcome of glioblastoma. In: De Vleeschouwer S (ed) Glioblastoma. Codon Publications, Brisbane

4. Cancer of the Brain and Other Nervous System—Cancer Stat Facts. SEER. https://seer.cancer.gov/statfacts/html/brain.html. Accessed 24 Mar 2022

5. Fernandes C et al (2017) Current standards of care in glioblastoma therapy. In: De Vleeschouwer S (ed) Glioblastoma. Codon Publications, Brisbane

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