Epidermal growth factor receptor (EGFR) amplification rates observed in screening patients for randomized trials in glioblastoma

Author:

Lassman Andrew B.ORCID,Aldape Kenneth D.,Ansell Peter J.,Bain Earle,Curran Walter J.,Eoli Marica,French Pim J.,Kinoshita Manabu,Looman Jim,Mehta Minesh,Muragaki Yoshihiro,Narita Yoshitaka,Ocampo Christopher,Roberts-Rapp Lisa,Song Minghao,Vogelbaum Michael A.,Walenkamp Annemiek M. E.,Wang Tony J. C.,Zhang Peixin,van den Bent Martin J.

Funder

AbbVie

NCI

Voices Against Brain Cancer

William Rhodes and Louise Tilzer-Rhodes Center for Glioblastoma at NewYork-Presbyterian Hospital

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Clinical Neurology,Neurology,Oncology

Reference20 articles.

1. Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, Barnholtz-Sloan J, Zou L, Vegesna R, Shukla SA, Ciriello G, Yung WK, Zhang W, Sougnez C, Mikkelsen T, Aldape K, Bigner DD, Van Meir EG, Prados M, Sloan A, Black KL, Eschbacher J, Finocchiaro G, Friedman W, Andrews DW, Guha A, Iacocca M, O'Neill BP, Foltz G, Myers J, Weisenberger DJ, Penny R, Kucherlapati R, Perou CM, Hayes DN, Gibbs R, Marra M, Mills GB, Lander E, Spellman P, Wilson R, Sander C, Weinstein J, Meyerson M, Gabriel S, Laird PW, Haussler D, Getz G, Chin L, Network TR (2013) The somatic genomic landscape of glioblastoma. Cell 155:462–477. https://doi.org/10.1016/j.cell.2013.09.034

2. Gan HK, Cvrljevic AN, Johns TG (2013) The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered. FEBS J 280:5350–5370. https://doi.org/10.1111/febs.12393

3. Yoshimoto K, Dang J, Zhu S, Nathanson D, Huang T, Dumont R, Seligson DB, Yong WH, Xiong Z, Rao N, Winther H, Chakravarti A, Bigner DD, Mellinghoff IK, Horvath S, Cavenee WK, Cloughesy TF, Mischel PS (2008) Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples. Clin Cancer Res 14:488–493. https://doi.org/10.1158/1078-0432.CCR-07-1966

4. van den Bent MJ, Gao Y, Kerkhof M, Kros JM, Gorlia T, van Zwieten K, Prince J, van Duinen S, Sillevis Smitt PA, Taphoorn M, French PJ (2015) Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas. Neuro Oncol 17:935–941. https://doi.org/10.1093/neuonc/nov013

5. Ahluwalia MS, Dimino C, Mansukhani MM, Murty VV, Canoll P, Narita Y, Muragaki Y, Gan HK, Merrell R, van den Bent MJ, Roberts-Rapp L, Jiang F, Guseva M, Bain EE, Ocampo CJ, Ansell PJ, Lassman AB (2018) Effect of therapeutic pressure on stability of EGFR amplification in glioblastoma. J Clin Oncol 36:2033. https://doi.org/10.1200/JCO.2018.36.15_suppl.2033

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