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A novel stem cell culture model of recurrent glioblastoma

  • Published:2015-10-23 Issue:1 Volume:126 Page:57-67
  • ISSN:0167-594X
  • Container-title:Journal of Neuro-Oncology
  • language:en
  • Short-container-title:J Neurooncol

Author:

Qazi Maleeha A.,Vora Parvez,Venugopal Chitra,McFarlane Nicole,Subapanditha Minomi K.,Murty Naresh K.,Hassell John A.,Hallett Robin M.,Singh Sheila K.

Funder

Canadian Institutes of Health Research (CA)

Terry Fox Research Institute (CA)

Stem Cell Network (CA)

Ontario Institute for Cancer Research (CA)

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Neurology (clinical),Neurology,Oncology

Reference32 articles.

1. Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O’Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM, Hayes DN, Cancer Genome Atlas Research N (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17:98–110. doi: 10.1016/j.ccr.2009.12.020

2. Wechsler-Reya R, Scott MP (2001) The developmental biology of brain tumors. Annu Rev Neurosci 24:385–428. doi: 10.1146/annurev.neuro.24.1.385

3. Zhu Y, Parada LF (2002) The molecular and genetic basis of neurological tumours. Nat Rev Cancer 2:616–626. doi: 10.1038/nrc866

4. Huse JT, Holland EC (2010) Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat Rev Cancer 10:319–331. doi: 10.1038/nrc2818

5. Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E, Mirimanoff RO, EuropeanOrganisation for R, Treatment of Cancer Brain T, Radiotherapy G, National Cancer Institute of Canada Clinical Trials G (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987–996. doi: 10.1056/NEJMoa043330

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