Overexpression of fatty acid synthase in human gliomas correlates with the WHO tumor grade and inhibition with Orlistat reduces cell viability and triggers apoptosis-Reference-Cited by-同舟云学术

Overexpression of fatty acid synthase in human gliomas correlates with the WHO tumor grade and inhibition with Orlistat reduces cell viability and triggers apoptosis

Published:2014-05-01 Issue:2 Volume:118 Page:277-287
ISSN:0167-594X
Container-title:Journal of Neuro-Oncology
language:en
Short-container-title:J Neurooncol

Author:

Grube Susanne,Dünisch Pedro,Freitag Diana,Klausnitzer Maren,Sakr Yasser,Walter Jan,Kalff Rolf,Ewald Christian

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Neurology (clinical),Neurology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s11060-014-1452-z.pdf

Reference46 articles.

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3. Kuhajda FP (2006) Fatty acid synthase and cancer: new application of an old pathway. Cancer Res 66:5977–5980. doi: 10.1158/0008-5472.CAN-05-4673

4. Menendez JA, Lupu R (2007) Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer 7:763–777. doi: 10.1038/nrc2222

5. Zhao W, Kridel S, Thorburn A, Kooshki M, Little J, Hebbar S, Robbins M (2006) Fatty acid synthase: a novel target for antiglioma therapy. Br J Cancer 95:869–878. doi: 10.1038/sj.bjc.6603350

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