Clinical and molecular features of patients with IDH1 wild-type primary glioblastoma presenting unexpected short-term survival after gross total resection

Author:

Toyoda Mariko,Shibahara Ichiyo,Shigeeda Ryota,Fujitani Kazuko,Tanihata Yoko,Hyakutake Yuri,Handa Hajime,Komai Hideto,Sato Sumito,Inukai Madoka,Hide Takuichiro,Shimoda Yoshiteru,Kanamori Masayuki,Endo Hidenori,Saito Ryuta,Matsuda Ken-Ichiro,Sonoda Yukihiko,Kumabe Toshihiro

Funder

Parents and Professors' Association, Kitasato University School of Medicine

Japan Society for the Promotion of Science

a Research Grant for young medical doctors and healthcare professionals from SRL

Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care

the Yokoyama Foundation for clinical pharmacology

Akaeda Medical Research Foundation

Uehara Memorial Foundation

Takeda Science Foundation

Taiju Life Social Welfare Foundation

Kitasato University AKPS

Publisher

Springer Science and Business Media LLC

Reference40 articles.

1. Burgenske DM, Yang J, Decker PA, Kollmeyer TM, Kosel ML, Mladek AC, Caron AA, Vaubel RA, Gupta SK, Kitange GJ, Sicotte H, Youland RS, Remonde D, Voss JS, Fritcher EGB, Kolsky KL, Ida CM, Meyer FB, Lachance DH, Parney IJ, Kipp BR, Giannini C, Sulman EP, Jenkins RB, Eckel-Passow JE, Sarkaria JN (2019) Molecular profiling of long-term IDH-wildtype glioblastoma survivors. Neuro Oncol 21:1458–1469. https://doi.org/10.1093/neuonc/noz129

2. Labussiere M, Boisselier B, Mokhtari K, Di Stefano AL, Rahimian A, Rossetto M, Ciccarino P, Saulnier O, Paterra R, Marie Y, Finocchiaro G, Sanson M (2014) Combined analysis of TERT, EGFR, and IDH status defines distinct prognostic glioblastoma classes. Neurology 83:1200–1206. https://doi.org/10.1212/WNL.0000000000000814

3. Weller M, Felsberg J, Hartmann C, Berger H, Steinbach JP, Schramm J, Westphal M, Schackert G, Simon M, Tonn JC, Heese O, Krex D, Nikkhah G, Pietsch T, Wiestler O, Reifenberger G, von Deimling A, Loeffler M (2009) Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol 27:5743–5750. https://doi.org/10.1200/JCO.2009.23.0805

4. Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M (2016) Association of the extent of resection with survival in glioblastoma: a systematic review and meta-analysis. JAMA Oncol 2:1460–1469. https://doi.org/10.1001/jamaoncol.2016.1373

5. Sanai N, Polley MY, McDermott MW, Parsa AT, Berger MS (2011) An extent of resection threshold for newly diagnosed glioblastomas. J Neurosurg 115:3–8. https://doi.org/10.3171/2011.2.JNS10998

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