Abstract
AbstractRecent developments in nanotechnology and nanoscience in all phases of human life have radically altered the diagnosis, treatment, and prevention of numerous diseases. Silver nanoparticles (Ag-NPs) have been among the most dynamic, and Several metallic nanoparticles developed for biological uses include some beautiful nanomaterials. Ag-NPs have played a pivotal role in nanotechnology and nanoscience, mostly nanomedicine. In this work, Ficus carica leaf extract was utilized to create silver nanoparticles using a straightforward procedure. This study explored the reduction of silver ions by F. carica leaf extract in the solution. UV–Vis spectroscopy, XRD analysis, and STEM characterize prepared biogenic Ag-NPs. Afterward, antibacterial and antibiofilm properties were investigated. The images obtained from STEM analysis surveyed that the NP sizes ranged from 11 to 20 nm. Ag-NPs demonstrated antibacterial and antibiofilm activities against all tested Gram-positive and Gram-negative bacteria strains. It has been indicated that Ag-NPs have inhibitory potency against collagenase activity. Ag-NPs exhibited anticancer activity in the HeLa cell line, and the IC50 value was calculated as 8.403 μg/mL. In this study, it has been shown that the synthesis method is environmentally friendly, fast, safe, and easy to use.
Publisher
Springer Science and Business Media LLC
Reference70 articles.
1. Ahmed S, Saifullah M, Ahmad BL, Swami SI (2016) Green synthesis of silver nanoparticles using Azadirachta indica aqueous leaf extract. J Radiat Res Appl Sci 9:1–7. https://doi.org/10.1016/j.jrras.2015.06.006
2. Ajitha B, Reddy YAK, Reddy PS (2015) Biosynthesis of silver nanoparticles using momordica charantia leaf broth: evaluation of their innate antimicrobial and catalytic activities. J Photochem Photobiol B 146:1–9
3. Ajitha B, Reddy YAK, Rajesh KM, Reddy PS (2016) Sesbania grandiflora leaf extract assisted green synthesis of silver nanoparticles: antimicrobial activity. Mater Today: Proc 3(6):1977–1984
4. Al-Sheddi ES, Farshori NN, Al-Oqail MM, et al (2018) Anticancer potential of green synthesized silver nanoparticles using extract of nepeta deflersiana against human cervical cancer cells (HeLA). Bioinorg Chem Appl
5. Andrews JM (2001) Determination of minimum inhibitory concentrations. J Antimicrob Chemother 48:5–16. https://doi.org/10.1093/jac/48.suppl_1.5
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