Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany

Author:

Dziodzio TomaszORCID,Hillebrandt Karl Herbert,Knitter Sebastian,Nösser Maximilian,Globke Brigitta,Ritschl Paul Viktor,Biebl Matthias,Denecke Christian,Raakow Jonas,Lurje Georg,Schöning Wenzel,Schmelzle Moritz,Kahl Andreas,Fütterer Markus,Budde Klemens,Eckardt Kai-Uwe,Halleck Fabian,Pratschke Johann,Öllinger Robert,Volker Assfalg,Anette Bachmann,Peter Benoehr,Adrian Billeter,Felix Braun,Jens Brockmann,Aydin Er,Susan Foller,Frank Friedersdorff,Andreas Fuehrer,Josef Geks,Klaus Grabitz,Martina Guthoff,Wilfried Gwinner,Fabian Halleck,Michael Heise,Uta Herden,Histros Karakizlis,Michael Keese,Stephan Kersting,Martina Koch,Markus Krautter,Uwe Kuhlmann,Christine Kurschat,Sven Lang,Lutz Liefeldt,Shanti Lokhande,Kai Lopau,Steffen Manekeller,Christian Mönch,Anja Mühlfeld,Silvio Nadalin,Martin Nitschke,Robert Öllinger,Mirian Opgenoorth,Ulrich Pein,Ursula Pession,Przemyslaw Pisarski,Juliane Putz,Thomas Rath,Peter Schenker,Daniel Seehofer,Stefan Siemer,Florian Sommer,Michael Stroehlein,Walter Treckmann Jürgen,Julia Weinmann-Menke,Peter Weithofer,Karl Wiegand,Daniel Zecher,

Abstract

Abstract Background Obesity in the recipient is linked to inferior transplant outcome. Consequently, access to kidney transplantation (KT) is often restricted by body mass index (BMI) thresholds. Bariatric surgery (BS) has been established as a superior treatment for obesity compared to conservative measures, but it is unclear whether it is beneficial for patients on the waiting list. Methods A national survey consisting of 16 questions was sent to all heads of German KT centers. Current situation of KT candidates with obesity and the status of BS were queried. Results Center response rate was 100%. Obesity in KT candidates was considered an important issue (96.1%; n = 49/51) and 68.6% (n = 35/51) of departments responded to use absolute BMI thresholds for KT waiting list access with ≥ 35 kg/m2 (45.1%; n = 23/51) as the most common threshold. BS was considered an appropriate weight loss therapy (92.2%; n = 47/51), in particular before KT (88.2%; n = 45/51). Sleeve gastrectomy was the most favored procedure (77.1%; n = 37/51). Twenty-one (41.2%) departments responded to evaluate KT candidates with obesity by default but only 11 (21.6%) had experience with ≥ n = 5 transplants after BS. Concerns against BS were malabsorption of immunosuppressive therapy (39.2%; n = 20/51), perioperative morbidity (17.6%; n = 9/51), and malnutrition (13.7%; n = 7/51). Conclusions Obesity is potentially limiting access for KT. Despite commonly used BMI limits, only few German centers consider BS for obesity treatment in KT candidates by default. A national multicenter study is desired by nearly all heads of German transplant centers to prospectively assess the potentials, risks, and safety of BS in KT waitlisted patients. Graphical abstract

Funder

Charité - Universitätsmedizin Berlin

Publisher

Springer Science and Business Media LLC

Subject

Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Surgery

Reference30 articles.

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