125I-labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (125I-OI5V) imaging visualized augmented sigma-1 receptor expression according to the severity of myocardial ischemia

Author:

Wakabayashi Hiroshi,Mori Hiroshi,Hiromasa Tomo,Akatani Norihito,Inaki Anri,Kozaka Takashi,Kitamura Yoji,Ogawa Kazuma,Kinuya Seigo,Taki Junichi

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging

Reference21 articles.

1. Shigeno T, Kozaka T, Kitamura Y, Ogawa K, Taki J, Kinuya S. In vitro and in vivo evaluation of [(125/123)I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([(125/123)I]-OI5V) as a potential sigma-1 receptor ligand for SPECT. Ann Nucl Med 2021;35:167‐75.

2. Stracina T, Novakova M. Cardiac sigma receptors: An update. Physiol Res 2018;67:S561‐76.

3. Su TP, Su TC, Nakamura Y, Tsai SY. The sigma-1 receptor as a pluripotent modulator in living systems. Trends Pharmacol Sci 2016;37:262‐78.

4. Penke B, Fulop L, Szucs M, Frecska E. The role of sigma-1 receptor, an intracellular chaperone in neurodegenerative diseases. Curr Neuropharmacol 2018;16:97‐116.

5. Vilner BJ, John CS, Bowen WD. Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines. Cancer Res 1995;55:408‐13.

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