Interference of 7-dehydrocholesterol in α-tocopherol determination by high-performance liquid chromatography: A possible screening test for the smith-lemli-opitz syndrome

Author:

Michel F.1,Cristol J. P.1,Vernet M. H.2,Feillet C.1,Carbonneau M. -A.1,Léger C. L.1,Castel J.2,Descomps B.13

Affiliation:

1. ; Laboratoire de Biologie et Biochimie des Lipides; Faculté de Médecine; Montpellier 34000 France

2. ; Laboratoire de Biochimie A; Hopital Lapeyronie; Av. G. Giraud Montpellier 34000 France

3. ; Lab. de Biologie et Biochimie des Lipides; Institut de Biologie; Bd Henri Montpellier IV-34060 France

Publisher

Wiley

Subject

Organic Chemistry,General Chemical Engineering

Reference10 articles.

1. Occurrence of Isomeric Dehydrocholesterols in Human Plasma;Axelson;J. Lipid Res.,1991

2. Abnormal Cholesterol Biosynthesis in the Smith-Lemli-Opitz Syndrome;Salen;Ibid.,1996

3. A Newly Organized Syndrome of Multiple Congenital Anomalies;Smith;J. Pediatr.,1964

4. Markedly Inhibited 7-Dehydrocholesterol Δ7-Reductase Activity in Liver Microsomes from Smith-Lemli-Opitz Homozygotes;Shefer;J. Clin. Invest.,1995

5. Diagnosis of Smith-Lemli-Opitz Syndrome;Seedorf;N. Engl. J. Med.,1994

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