Enantioselective steady-state kinetics of unbound disopyramide and its dealkylated metabolite in man
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF00626374.pdf
Reference18 articles.
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2. Mirro MJ, Watanabe AM, Bailey JC (1981) Electrophysiological effects of the optimal isomers of disopyramide and quinidine in the dog. Dependence on stereochemistry. Circ Res 48: 867?874
3. Burke TR Jr, Nelson WL, Mangion M, Hite GJ, Mokler CM, Ruenitz PC (1980) Resolution, absolute configuration, and anti-arrhythmic properties of the enantiomers of disopyramide, 4-(diisopropylamino)-2-(2-pyridyl)-2-phenylbutyramide. J. Med Chem 23: 1044?1048
4. Pollick C, Giacomini KM, Blaschke TF, Nelson WL, Turner-Tamiyasu K, Briskin V, Popp RL (1982) The cardiac effects of d- and 1-disopyramide in normal subjects: a noninvasive study. Circulation 66: 447?453
5. Giacomini KM, Cox BM, Blaschke TF (1980) Comparative anticholinergic potencies of R- and S-disopyramide in longitudinal muscle strips from guinea pig ileum. Life Sci 27: 1191?1197
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