CAR T cells equipped with a fully human scFv targeting Trop2 can be used to treat pancreatic cancer-Reference-Cited by-同舟云学术

CAR T cells equipped with a fully human scFv targeting Trop2 can be used to treat pancreatic cancer

Published:2022-04-21 Issue:9 Volume:148 Page:2261-2274
ISSN:0171-5216
Container-title:Journal of Cancer Research and Clinical Oncology
language:en
Short-container-title:J Cancer Res Clin Oncol

Author:

Zhu Hongjia^ORCID,Fang Xiaoyan,Tuhin Israth Jahan,Tan Jingwen,Ye Jing,Jia Yujie,Xu Nan,Kang Liqing,Li Minghao,Lou XiaoYan,Zhou Jing-e,Wang Yiting,Yan Zhiqiang,Yu Lei

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00432-022-04017-x.pdf

Reference39 articles.

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2. Brudno JN, Lam N, Vanasse D, Shen YW, Rose JJ, Rossi J, Xue A, Bot A, Scholler N, Mikkilineni L et al (2020) Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma. Nat Med 26:270–280

3. Cardillo TM, Govindan SV, Sharkey RM, Trisal P, Arrojo R, Liu D, Rossi EA, Chang CH, Goldenberg DM (2015) Sacituzumab Govitecan (IMMU-132), an anti-trop-2/SN-38 antibody-drug conjugate: characterization and efficacy in pancreatic, gastric, and other cancers. Bioconjug Chem 26:919–931

4. Chen H, Wei F, Yin M, Zhao Q, Liu Z, Yu B, Huang Z (2021) CD27 enhances the killing effect of CAR T cells targeting trophoblast cell surface antigen 2 in the treatment of solid tumors. Cancer Immunol Immunother 70:2059–2071

5. Cubas R, Li M, Chen C, Yao Q (2009) Trop2: a possible therapeutic target for late stage epithelial carcinomas. Biochim Biophys Acta 1796:309–314

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