Neferine, a novel ROCK1-targeting inhibitor, blocks EMT process and induces apoptosis in non-small cell lung cancer-Reference-Cited by-同舟云学术

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Neferine, a novel ROCK1-targeting inhibitor, blocks EMT process and induces apoptosis in non-small cell lung cancer

Published:2022-08-19 Issue:2 Volume:149 Page:553-566
ISSN:0171-5216
Container-title:Journal of Cancer Research and Clinical Oncology
language:en
Short-container-title:J Cancer Res Clin Oncol

Author:

Hu Po^ORCID,Wan Peng,Xu Anna,Yan Binghui,Liu Chunmei,Xu Qixuan,Wei Zhenhuan,Xu Jingyi,Liu Siqi,Yang Guangming,Pan Yang

Funder

Priority Academic Program Development of Jiangsu Higher Education Institutions

Top-notch Academic Programs Project of Jiangsu Higher Education Institutions

Innovative Research Group Project of the National Natural Science Foundation of China

the Open Project of State Key Laboratory of Natural Medicines

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00432-022-04280-y.pdf

Reference45 articles.

1. Adachi Y, Ito K, Hayashi Y et al (2020) Epithelial-to-mesenchymal transition is a cause of both intrinsic and acquired resistance to KRAS G12C inhibitor in KRAS G12C-mutant non-small cell lung cancer. Clin Cancer Res 26(22):5962–5973. https://doi.org/10.1158/1078-0432.CCR-20-2077

2. Adderley H, Blackhall FH, Lindsay CR (2019) KRAS-mutant non-small cell lung cancer: converging small molecules and immune checkpoint inhibition. EBioMedicine 41:711–716. https://doi.org/10.1016/j.ebiom.2019.02.049

3. Barbacid M (2012) Opening a new GATAway for treating KRAS-driven lung tumors. Cancer Cell 21(5):598–600. https://doi.org/10.1016/j.ccr.2012.04.032

4. de Sousa GR, Vieira GM, das ChagasPezuk PFJA, Brassesco MS (2020) Should we keep rocking? Portraits from targeting Rho kinases in cancer. Pharmacol Res 160:105093. https://doi.org/10.1016/j.phrs.2020.105093

5. Deng G, Zeng S, Ma J et al (2017) The anti-tumor activities of Neferine on cell invasion and oxaliplatin sensitivity regulated by EMT via Snail signaling in hepatocellular carcinoma. Sci Rep 7:41616. https://doi.org/10.1038/srep41616

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