CSMed® wound dressing for prophylaxis and management of radiation dermatitis in breast and head–neck cancer patients: a single hospital prospective clinical trial

Author:

Lee Yueh-Chun,Tseng Hsien-Chun,Yang Huei-Fang,Lee Yi-Hung,Ko Ya-Fang,Chang Shin-Tsung,Chen Hsin-Lin,Chang Bo-Jiun,Chou Ying-Hsiang

Abstract

Abstract Purpose CSMed® wound dressing, a dressing with various herb extracts, was tested for its therapeutic effect in radiation dermatitis of breast and head-and-neck cancer patients. Methods This study included 20 breast cancer patients and 10 head-and-neck cancer patients. Half of the irradiated area was covered with CSMed® and the other half was under routine treatment. The severity of radiation dermatitis was evaluated with radiation therapy oncology group (RTOG) grade throughout the treatment and the follow-up period. The RTOG grade between the dressed and undressed area were compared to illustrate the therapeutic effect of CSMed® dressing. Results The results showed that CSMed® dressed area had significant lower RTOG score at 3–7 weeks and final record during the treatment, and 1–3 weeks during follow-up than undressed area. Conclusions This indicated that CSMed® can delay the onset, reduce the severity, and enhance healing of radiation dermatitis. CSMed® can be used for prophylaxis and management of radiation dermatitis.

Publisher

Springer Science and Business Media LLC

Reference30 articles.

1. Arribas-López E, Zand N, Ojo O, Snowden MJ, Kochhar T (2022) A systematic review of the effect of Centella asiatica on wound healing. Int J Environ Res Public Health 19(6):3266

2. Asha KK, Thomas S (2019) Recent advances on herb-derived constituents-incorporated wound-dressing materials: a review. Polym Adv Technol 4:823–839

3. Bae SR, Park C, Choi JC, Poo H, Kim CJ, Sung MH (2010) Effects of ultra high molecular weight poly-gamma-glutamic acid from Bacillus subtilis (chungkookjang) on corneal wound healing. J Microbiol Biotechnol 20(4):803–808

4. Brinkhaus B, Lindner M, Schuppan D, Hahn EG (2000) Chemical, pharmacological and clinical profile of the East Asian medical plant Centella asiatica. Phytomedicine 7(5):427–448

5. Bunyapraphatsara N, Jirakulchaiwong S, Thirawarapan S, Manonukul J (1996) The efficacy of Aloe vera cream in the treatment of first, second and third degree burns in mice. Phytomedicine 2(3):247–251

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3