Epothilone B induces apoptosis and enhances apoptotic effects of ABT-737 on human cancer cells via PI3K/AKT/mTOR pathway-Reference-Cited by-同舟云学术

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Epothilone B induces apoptosis and enhances apoptotic effects of ABT-737 on human cancer cells via PI3K/AKT/mTOR pathway

Published:2016-09-03 Issue:11 Volume:142 Page:2281-2289
ISSN:0171-5216
Container-title:Journal of Cancer Research and Clinical Oncology
language:en
Short-container-title:J Cancer Res Clin Oncol

Author:

Li Yang-ling,Sun Jiao,Hu Xiu,Pan Yi-ni,Yan Wei,Li Qing-yu,Wang Fei,Lin Neng-ming,Zhang Chong

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Public-Service Technology Research Plan of Zhejiang Province

High-level Talents Coming Back From Abroad Innovation and Entrepreneurship Program in Hangzhou

Zhejiang Provincial Program for the Cultivation of High-level Innovative Health talents

Scientific and Technological Developing Scheme of Hangzhou City

Hang-zhou 131 Talents Project

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00432-016-2236-y.pdf

Reference36 articles.

1. Albrethsen J, Angeletti RH, Horwitz SB, Yang CP (2014) Proteomics of cancer cell lines resistant to microtubule-stabilizing agents. Mol Cancer Ther 13:260–269. doi: 10.1158/1535-7163.MCT-13-0471

2. Argyriou AA, Marmiroli P, Cavaletti G, Kalofonos HP (2011) Epothilone-induced peripheral neuropathy: a review of current knowledge. J Pain Symptom Manage 42:931–940. doi: 10.1016/j.jpainsymman.2011.02.022

3. Ashkenazi A (2008) Targeting the extrinsic apoptosis pathway in cancer. Cytokine Growth Factor Rev 19:325–331. doi: 10.1016/j.cytogfr.2008.04.001

4. Asnaghi L et al (2004) Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt. Oncogene 23:5781–5791. doi: 10.1038/sj.onc.1207698

5. Baumgart T, Kriesen S, Neels O, Hildebrandt G, Manda K (2015) Investigation of epothilone B-induced cell death mechanisms in human epithelial cancer cells-in consideration of combined treatment with ionizing radiation. Cancer Invest 33:213–224. doi: 10.3109/07357907.2015.1020115

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