A comprehensive prognostic analysis of osimertinib treatment in advanced non-small cell lung cancer patients with acquired EGFR-T790M mutation: a real-world study

Author:

Tang Xin,Li Yuan,Qian Wen-lei,Yan Wei-feng,Pang Tong,Gong You-ling,Yang Zhi-gangORCID

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Reference34 articles.

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2. Ballard P, Yates JW, Yang Z, Kim DW, Yang JC, Cantarini M, Pickup K, Jordan A, Hickey M, Grist M, Box M, Johnström P, Varnäs K, Malmquist J, Thress KS, Jänne PA, Cross D (2016) Preclinical comparison of osimertinib with other EGFR-TKIs in EGFR-mutant NSCLC brain metastases models, and early evidence of clinical brain metastases activity. Clin Cancer Res 22(20):5130–5140. https://doi.org/10.1158/1078-0432.Ccr-16-0399

3. Campo M, Gerber D, Gainor JF, Heist RS, Temel JS, Shaw AT, Fidias P, Muzikansky A, Engelman JA, Sequist LV (2016) Acquired resistance to first-line afatinib and the challenges of prearranged progression biopsies. J Thorac Oncol 11(11):2022–2026. https://doi.org/10.1016/j.jtho.2016.06.032

4. Chen Y, Wang S, Zhang B, Zhao Y, Zhang L, Hu M, Zhang W, Han B (2020) Clinical factors affecting the response to osimertinib in non-small cell lung cancer patients with an acquired epidermal growth factor receptor T790M mutation: a long-term survival analysis. Target Oncol 15(3):337–345. https://doi.org/10.1007/s11523-020-00724-y

5. Cross DA, Ashton SE, Ghiorghiu S, Eberlein C, Nebhan CA, Spitzler PJ, Orme JP, Finlay MR, Ward RA, Mellor MJ, Hughes G, Rahi A, Jacobs VN, Red Brewer M, Ichihara E, Sun J, Jin H, Ballard P, Al-Kadhimi K, Rowlinson R, Klinowska T, Richmond GH, Cantarini M, Kim DW, Ranson MR, Pao W (2014) AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov 4(9):1046–1061. https://doi.org/10.1158/2159-8290.Cd-14-0337

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