Hematopoietic stem cells suppress proliferation and enhance differentiation of leukemia cells through regulating apoptotic and inflammatory genes

Author:

Li Bo,Can Can,Liu Wancheng,Guo Xiaodong,Wu Hanyang,Wei Yihong,Liu Jinting,Yang Xinyu,Jia Wenbo,Ma Daoxin

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Reference24 articles.

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2. Chen F, Zhou K, Zhang L, Ma F, Chen D, Cui J, Feng X, Yang S, Chi Y, Han Z, Xue F, Rong L, Ge M, Wan L, Xu S, Du W, Lu S, Ren H, Han Z (2013) Mesenchymal stem cells induce granulocytic differentiation of acute promyelocytic leukemic cells via IL-6 and MEK/ERK pathways. Stem Cells Dev. 22(13):1955–1967. https://doi.org/10.1089/scd.2012.0621. (PMID: 23391335; PMCID: PMC3685326)

3. Chen YC, Lan YW, Huang SM, Yen CC, Chen W, Wu WJ, Staniczek T, Chong KY, Chen CM (2022) Human amniotic fluid mesenchymal stem cells attenuate pancreatic cancer cell proliferation and tumor growth in an orthotopic xenograft mouse model. Stem Cell Res Ther 13(1):235. https://doi.org/10.1186/s13287-022-02910-3.PMID:35659367;PMCID:PMC9166578

4. Cordingley FT, Bianchi A, Hoffbrand AV, Reittie JE, Heslop HE, Vyakarnam A, Turner M, Meager A, Brenner MK (1988) Tumour necrosis factor as an autocrine tumour growth factor for chronic B-cell malignancies. Lancet 1(8592):969–971. https://doi.org/10.1016/s0140-6736(88)91782-5. (PMID: 2896830)

5. Gauthaman K, Yee FC, Cheyyatraivendran S, Biswas A, Choolani M, Bongso A (2012) Human umbilical cord Wharton’s jelly stem cell (hWJSC) extracts inhibit cancer cell growth in vitro. J Cell Biochem 113(6):2027–2039. https://doi.org/10.1002/jcb.24073. (PMID: 22275115)

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