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CD4 levels and NSCLC metastasis: the benefits of maintaining moderate levels

  • Published:2023-09-21 Issue:18 Volume:149 Page:16827-16836
  • ISSN:0171-5216
  • Container-title:Journal of Cancer Research and Clinical Oncology
  • language:en
  • Short-container-title:J Cancer Res Clin Oncol

Author:

Bai Ying,Liu Yafeng,Wu Jing,Miao Rui,Xu Zhi,Hu Chunxiao,Zhou Jiawei,Guo Jianqiang,Xie Jun,Shi Zilun,Ding Xuansheng,Xing Yingru,Hu Dong

Funder

Open Research Fund of Anhui Province Engineering Laboratory of Occupational Health and Safety

Graduate Innovation Foundation of AUST

the Collaborative Innovation Project of Colleges and Universities of Anhui Province

the National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Reference24 articles.

1. Anichini A, Perotti VE, Sgambelluri F, Mortarini R (2020) Immune escape mechanisms in non small cell lung cancer. Cancers (Basel). https://doi.org/10.3390/cancers12123605

2. Asselain B, Barriere JR, Clarot C, Vabre JP, Gentil LPB, Duval Y, Thomas P, Herman D, Grivaux M, Debieuvre D (2019) Metastatic NSCLC: clinical, molecular, and therapeutic factors associated with long-term survival. Respir Med Res 76:38–44. https://doi.org/10.1016/j.resmer.2019.07.001

3. Braumuller H, Wieder T, Brenner E, Assmann S, Hahn M, Alkhaled M, Schilbach K, Essmann F, Kneilling M, Griessinger C, Ranta F, Ullrich S, Mocikat R, Braungart K, Mehra T, Fehrenbacher B, Berdel J, Niessner H, Meier F, van den Broek M, Haring HU, Handgretinger R, Quintanilla-Martinez L, Fend F, Pesic M, Bauer J, Zender L, Schaller M, Schulze-Osthoff K, Rocken M (2013) T-helper-1-cell cytokines drive cancer into senescence. Nature 494:361–365. https://doi.org/10.1038/nature11824

4. Burt P, Peine M, Peine C, Borek Z, Serve S, Flossdorf M, Hegazy AN, Hofer T, Lohning M, Thurley K (2022) Dissecting the dynamic transcriptional landscape of early T helper cell differentiation into Th1, Th2, and Th1/2 hybrid cells. Front Immunol 13:928018. https://doi.org/10.3389/fimmu.2022.928018

5. Chae YK, Chang S, Ko T, Anker J, Agte S, Iams W, Choi WM, Lee K, Cruz M (2018) Epithelial–mesenchymal transition (EMT) signature is inversely associated with T-cell infiltration in non-small cell lung cancer (NSCLC). Sci Rep 8:2918. https://doi.org/10.1038/s41598-018-21061-1
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