Are Generic Drugs Used in Cardiology as Effective and Safe as their Brand-name Counterparts? A Systematic Review and Meta-analysis

Author:

Leclerc JacintheORCID,Thibault Magalie,Midiani Gonella Jennifer,Beaudoin Claudia,Sampalis John

Funder

Ministere de l'economie et de l'innovation

Canadian Heart Failure Society

Quebec Heart Failure Society

Université du Québec à Trois-Rivières

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical)

Reference86 articles.

1. Association Canadienne du Médicament Générique. Les faits. 2017. http://generiquescanadiens.ca/les-faits/medicaments-generiques/. Accessed 27 septembre 2017

2. Santé Canada. Ligne directrice - Normes en matière d’études de biodisponibilités comparatives: Formes pharmaceutiques de médicaments à effets systémiques. 2018. https://www.canada.ca/fr/sante-canada/services/medicaments-produits-sante/medicaments/demandes-presentations/lignes-directrices/biodisponibilite-bioequivalence/normes-matiere-etudes-biodisponibilite-comparatives-formes-pharmaceutiques-medicaments-effets-systemiques.html. Accessed 29 octobre 2018

3. Leclerc J, Blais C, Rochette L, et al. Did Generic Clopidogrel Commercialization Affect Trends of ER Consultations and Hospitalizations in the Population Treated with Clopidogrel? Drugs Aging. 2019.

4. Leclerc J, Blais C, Rochette L, et al. Trends in hospital visits for generic and brand-name warfarin users in Quebec, Canada; a population-based time series analysis. Am J Cardiovasc Drugs. 2018;19(3):287–97.

5. Leclerc J, Blais C, Rochette L, et al. Impact of the commercialization of three generic angiotensin II receptor blockers on adverse events in Quebec, Canada: a population-based time series analysis. Circ Cardiovasc Qual Outcomes. 2017;10:1–9.

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