In Silico Identification of Piperazine Linked Thiohydantoin Derivatives as Novel Androgen Antagonist in Prostate Cancer Treatment

Author:

Bhati Shipra,Kaushik Vikas,Singh JoginderORCID

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Molecular Medicine,Biochemistry,Bioengineering,Analytical Chemistry

Reference54 articles.

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2. Abubshait SA (2017) Synthesis, antimicrobial and anticancer activities of some 2-thiohydantoin derivatives. Ind J Chem 56(B):641–648

3. American Cancer Society (2017) Cancer facts & figures. Available from: http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2017/index . Accessed 25 Dec 2017

4. Balakin KV, Ivanenkov YA, Savchuk NP, Ivashchenko AA, Ekins S (2005) Comprehensive computational assessment of ADME properties using mapping techniques. Curr Drug Discov Technol 2(2):99–113

5. Barton VN, D’Amato NC, Gordon MA (2015) Multiple molecular subtypes of triple-negative breast cancer critically rely on androgen receptor and respond to enzalutamide in vivo. Mol Cancer Ther 14(3):769–778

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