Point Mutation Approach to Reduce Antigenicity of Interferon Beta-Reference-Cited by-同舟云学术

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Point Mutation Approach to Reduce Antigenicity of Interferon Beta

Published:2019-10-08 Issue:3 Volume:26 Page:1353-1361
ISSN:1573-3149
Container-title:International Journal of Peptide Research and Therapeutics
language:en
Short-container-title:Int J Pept Res Ther

Author:

Haji Abdolvahab Mohadeseh,Venselaar Hanka,Fazeli Ahmad,Arab S. Shahriar,Behmanesh Mehrdad

Funder

Ministry of Science Research and Technology of IRAN

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Molecular Medicine,Biochemistry,Bioengineering,Analytical Chemistry

Link

http://link.springer.com/content/pdf/10.1007/s10989-019-09938-9.pdf

Reference55 articles.

1. Abdolvahab MH, Brinks V, Schellekens H (2014) A modified immune tolerant mouse model to study the immunogenicity of recombinant human interferon beta. J Immunol Methods 415:17–23. https://doi.org/10.1016/j.jim.2014.10.004

2. Abdolvahab MH, Fazeli A, Halim A et al (2016) Immunogenicity of recombinant human interferon beta-1b in immune-tolerant transgenic mice corresponds with the biophysical characteristics of aggregates. J Interferon Cytokine Res 36:247–257. https://doi.org/10.1089/jir.2015.0108

3. Amartely H, Iosub-Amir A, Friedler A (2014) Identifying protein-protein interaction sites using peptide arrays. J Vis Exp. https://doi.org/10.3791/52097

4. Andresen H, Zarse K, Grotzinger C et al (2006) Development of peptide microarrays for epitope mapping of antibodies against the human TSH receptor. J Immunol Methods 315:11–18. https://doi.org/10.1016/j.jim.2006.06.012

5. Asgari S, Ebrahim-Habibi A, Mahdavi M et al (2017) Therapeutic protein deimmunization by T-cell epitope removal: antigen-specific immune responses in vitro and in vivo. APMIS 125:544–552. https://doi.org/10.1111/apm.12682

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