Differences in Action of PACAP-27 and PACAP-38 on Guinea Pig Gallbladder Smooth Muscle Using Synthetic C-terminally Modified PACAP Peptides

Author:

Wei Mu-xin,Naruse Satoru,Ozaki Tsuyoshi,Hu Ping,Wray Victor,Nokihara Kiyoshi

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Molecular Medicine,Biochemistry,Bioengineering,Analytical Chemistry

Reference15 articles.

1. Ando E, Nokihara K, Naruse S (1994) Development of pituitary adenylate cyclase activating polypeptides (PACAPs) specific radioimmunoassay systems and distribution of PACAP-like immunoreactivity in guinea pig tissues. Biomed Pept Proteins Nucleic Acids 1:45–50

2. Ando E, Nokihara K, Naruse S, Wray V (1996) Recognition of pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide (PACAP/VIP) hybrids and related peptides by rat brain membranes. Biomed Pept Proteins Nucleic Acids 2:41–46

3. Arimura A (1992) Pituitary adenylate cyclase activating polypeptide (PACAP): discovery and current status of research. Regul Pept 37:287–303

4. Fry DC, Madison VS, Bolin DR, Greeley DN, Toome V, Wegrzynski BB (1989) Solution structure of an analogue of vasoactive intestinal peptide as determined by two-dimensional NMR and circular dichroism spectroscopies and constrained molecular dynamics. Biochemistry 28:2399–2409

5. Lauff JM, Modlin IM, Tang LH (1999) Biological relevance of pituitary adenylate cyclase-activating polypeptide (PACAP) in the gastrointestinal tract. Regul Pept 84:1–12

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